Persistent EBNA-1 peptide IgG antibody levels may help distinguish multiple sclerosis from other neuroinflammatory diseases like MOGAD and NMOSD. Neuromyelitis optica, also known as NMO, is a central nervous system disorder that causes inflammation in nerves of the eye and the spinal cord. NMO also is called neuromyelitis optica spectrum disorder (NMOSD) and Devic disease.
It occurs when the immune system reacts against the body's own cells. Neuromyelitis optica (NMO) is a particular disease within the NMOSD spectrum. It is characterised by optic neuritis and longitudinally extensive myelitis. In more than 80% of NMO cases, the cause is immunoglobulin G autoantibodies to aquaporin 4 (anti-AQP4), the most abundant water channel protein in the central nervous system.
nmo neurological disease, [5][1][4] Neuromyelitis optica spectrum disorder (NMOSD; previously known as Devic disease or neuromyelitis optica [NMO]) is an inflammatory disorder of the central nervous system characterized by severe, immune-mediated demyelination and axonal damage predominantly targeting optic nerves and the spinal cord. Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease. It causes multifocal central nervous system (CNS) inflammation that primarily affects the optic nerves and spinal... Neuromyelitis optica (NMO) is an inflammatory disease that causes demyelination of the central nervous system, primarily affecting the optic nerve (optic neuritis) and the spinal cord. Neuromyelitis optica spectrum disorder (NMOSD) is a rare and severe inflammatory autoimmune disease of the central nervous system (CNS) that was identified as a distinct clinical entity with the discovery of aquaporin-4 immunoglobulin G antibodies (AQP4-IgG) [90, 124, 137].
nmo neurological disease, Neurology Advisor: EBV Antibody Titers May Distinguish MS From Other Neurologic Diseases
